Leadership

We’re people people. We’ve handpicked our team to ensure each individual’s strengths further the pursuit of our shared goal to change patients’ lives.

Meet the executive team

Headshot of John Shannon
John Shannon
Chief Executive Officer

John Shannon was appointed Chief Executive Officer in August 2024.  He joined Xeris in 2017 as Chief Operating Officer and was promoted to President in 2020.  Mr. Shannon has 35+ years of pharmaceutical and healthcare experience with a diverse background in sales, global and US marketing, operations and manufacturing, strategic planning, and business development.

Prior to Xeris, Mr. Shannon spent two years as Chief Executive Officer for Catheter Connections, Inc., a company focused on the development and commercialization of innovative vascular access products designed to protect patients from acquiring infections during intravenous infusion therapy. Catheter Connections, Inc. was acquired by Merit Medical in January 2016.

Before Catheter Connections, Mr. Shannon spent three years as Chief Commercial Officer for Durata Therapeutics, a biopharmaceutical company focused on the development and commercialization of differentiated therapeutic solutions to advance patient care in infectious disease and acute illnesses. Durata was acquired by Actavis (now Allergan) in November 2014. Mr. Shannon spent 10 years (2001–2011) at Baxter Healthcare, where he was General Manager, Global Hemophilia and Global Commercial Excellence; General Manager, US Biopharmaceuticals; Vice President, Marketing US Bioscience; and Vice President, Marketing US Renal. During his time at Baxter, he led the commercialization and drove the growth of two Baxter brands, ADVATE® and GAMMAGARD®, both of which now exceed revenues of $1 billion.

Prior to coming to Baxter, Mr. Shannon was Vice President, Marketing for Caremark. Before that, he was at Searle for 10 years; there, he held several positions, most notably Executive Director, Cardiovascular Global Commercialization, in which he was responsible for the commercial development and marketing of new cardiovascular products worldwide, and Senior Director of Cox-2 Global Commercialization, in which he led the worldwide launch and global marketing of Celebrex®. In addition, he spent 7 years at Bock Pharmacal Company, where he held various positions including Sales Representative, Sales Trainer, Sales Operations, Marketing, Strategic Planning, and Business Development.

Mr. Shannon holds a BS in Biology with an emphasis in Microbiology from Western Illinois University.

Headshot of Kevin McCulloch
Kevin McCulloch
President and Chief Operating Officer

Kevin McCulloch was named President and Chief Operating Officer of Xeris in August 2024.  He joined Xeris Pharmaceuticals in October 2018 as Senior Vice President, Global Operations and Business Development and was named Chief Commercial Officer in September 2021. Mr. McCulloch has spent more than 35 years in the pharmaceutical and medical device industry in diverse leadership and general management roles spanning sales, marketing, and business operations for both US and international entities.

Prior to joining Xeris, Kevin was the President of Global Solutions at Hill-Rom and earlier, as Chief Business Officer for Water Street Healthcare Partners Pharmaceutical Holdings. Mr. McCulloch spent 15 years with Baxter Healthcare in successive management roles including GM/President of the Global Services, Global Fluid Systems (GFS), Infusion Systems (IS), and Fenwal business units. While the leader of GFS, he created Celerity Pharmaceuticals, one of the industry’s first R&D externalization ventures that has since successfully generated multiple new product launches. As leader of the IS business, he oversaw the acquisition and integration of Sigma International into the IS portfolio while successfully navigating the business out of a long-standing consent decree. As the President of Fenwal, a global leader in blood collection and apheresis technology, Mr. McCulloch led its successful divestiture to TPG in 2007. He started his Baxter career as a Vice President of Global Marketing in the Renal division. Prior to Baxter, Mr. McCulloch spent 9 years at GD Searle in roles of increasing responsibility in business development, marketing, and sales. He began his career as a territory sales representative with the Upjohn Company.

Mr. McCulloch holds an MBA from Northwestern University’s Kellogg School of Management and a BS in Biology from the University of Michigan.
 

Headshot of Anh  Nguyen, MD, MBA
Anh Nguyen, MD, MBA
Chief Medical Officer

Dr. Anh Nguyen serves as Chief Medical Officer, leading clinical development, regulatory strategy, and medical affairs to advance innovative therapies for patients with rare diseases and complex conditions. With a strong focus on translational medicine and patient-centered drug development, Dr. Nguyen drives cross-functional collaboration to bring next-generation therapies from discovery to commercialization.  

Dr. Nguyen has more than 20 years of experience spanning biopharmaceutical leadership across small molecules, biologics, RNA therapeutics, and cell and gene therapies. His experience spans early through late-stage drug development and commercial launch - including drug discovery, translation medicine, CMC, regulatory affairs, clinical development, medical affairs, pharmacovigilance, and market access. He led multiple IND submissions for first-in-class therapies, including circular RNA treatments for oncology, immuno-oncology vaccines, gene-edited solid organ xenotransplants, and allogeneic CAR-T therapies. Prior he was Vice President, Therapeutic Sector Lead at Asklepios Biopharmaceutical (AskBio), where he guided the IND clearance and early-phase clinical trials for AAV gene therapies targeting heart failure and neuromuscular rare disease.  

Dr. Nguyen also held key leadership roles at Xeris Pharmaceuticals, where he served as Program Medical Lead for Gvoke®’s NDA and MAA approvals and multiple IND clearances in endocrine and rare disease indications. Earlier in his career, he served as Global Medical Director at Baxter Healthcare, where he oversaw clinical trials and regulatory submissions for drugs, devices, and biologics across immunology, nephrology, pulmonology, cardiovascular, and digital health.  

Dr. Nguyen has deep expertise in federal regulatory and policy development, having served as a Medical Officer and clinical reviewer at the U.S. Food and Drug Administration (FDA) and the Centers for Medicare and Medicaid Services (CMS). At the FDA, he contributed to regulatory strategy, combination product approvals, and policy guidance for digital health and combination products. While at CMS, he conducted coverage analyses for novel therapeutics and helped shape Medicare policy. As a Robert Wood Johnson Foundation Health Policy Fellow and Senate Committee Staffer, Dr. Nguyen played a pivotal role in drafting components of the landmark "21st Century Cures Act", which strengthened U.S. biomedical innovation and became law in 2016.  

Dr. Nguyen’s commitment to advancing medical science was further recognized during his tenure at the National Institutes of Health (NIH), where he led the establishment of an ambulatory surgical service to expedite pediatric orphan disease and oncology trials. His contributions in developing and executing early-stage pediatric trials in oncology, neurology, and rare metabolic disorders earned him the prestigious NIH Director’s Award.  

Dr. Nguyen holds an MD from Rutgers New Jersey Medical School and an MBA with a concentration in finance from the University of Chicago Booth School of Business. He completed his residency and fellowship training in anesthesiology and cardiovascular anesthesia at Massachusetts General Hospital, Harvard Medical School.

Meet the board of directors

Headshot of Marla S.  Persky
Marla S. Persky
Independent, Non-executive Chairperson of the Board

Marla Persky is CEO and President of WOMN LLC, a company dedicated to helping women succeed in the business of law by increasing their knowledge of and acuity with financial drivers, client development, and leadership. Throughout her professional life, Ms. Persky has had the opportunity to understand and practice business principles that lead to personal and company success. Ms. Persky retired in 2013 as Senior Vice President, General Counsel and Corporate Secretary for Boehringer Ingelheim USA, where she oversaw a department of over 70 individuals. She also was a member of Boehringer’s executive management team and a director of the company and several of its subsidiaries.

Prior to joining Boehringer Ingelheim, Ms. Persky spent 19 years at Baxter International Inc. where she held numerous business and legal positions, the most recent of which was Acting General Counsel and Corporate Secretary. During her career at Baxter, Ms. Persky managed global legal services, was General Manager of an international medical device business, led international crisis management teams, acquired and integrated international businesses, and designed/implemented strategies to manage global mass torts.

Ms. Persky is currently a member of the board of directors of Revolo Biotherapeutics, a venture funded biotechnology company engaged in the development of therapies that reset the immune system to achieve long-term disease remission. Previously, she served on the board of directors of Cytyc Corporation (Nasdaq listed diagnostics company) Panavance Therapeutics Inc (clinical-stage pharmaceutical company). She was also on the board of Boehringer Ingelheim Corporation, the world’s largest privately owned pharmaceutical company. Ms. Persky was a director of Watermark, Inc., a private publisher and broker of children’s literature.

In addition to her corporate activities, Ms. Persky is on the board of several not-for-profit organizations such as the Leukemia & Lymphoma Society, Primary Stages (an off- Broadway theater company), and the Ridgefield Symphony Orchestra. Ms. Persky is a frequent speaker on a variety of subjects, including leadership principles, mentoring, diversity, crisis management, and negotiation techniques.

Throughout her career, Ms. Persky has focused on improving diversity and inclusion in the legal profession. She has been awarded for her contributions by elite organizations such as the Lawyer's Collaborative for Diversity and the Connecticut Appleseed Foundation. She was recognized as one of the 10 most innovative in-house counsels for her strategy and efforts to increase the opportunities and visibility of women in high-profile litigation

She is a graduate of the Washington University School of Law and Northwestern University.


Committee Roles:
Chair of the Board
Member of the Audit Committee
Member of Nominating Governance Committee
 

Headshot of James Brady
James Brady
Independent, Non-executive Board Member

James Brady is an experienced international business executive who served in multiple leadership roles of increasing responsibility for AstraZeneca prior to his retirement. His more than thirty years of progressive experience at AstraZeneca included successful national, regional and global finance roles in corporate operations, manufacturing, commercial, marketing, market access, audit, international business, and biologics discovery & development. James most recently served as Chief Financial Officer of MedImmune, the biologics discovery and development division of AstraZeneca. During his tenure at MedImmune, biologics grew to represent more than half of the product development portfolio of AstraZeneca and five biologics were successfully brought to market. Throughout his career at AstraZeneca, James had P&L and management responsibilities for significant operating units and finance functions including MedImmune, the Asia Pacific Region, US Government, Policy and Managed Markets, and Global Marketing. James also served as the Chief Audit Executive for AstraZeneca. His experience spans the full product development cycle from early research and clinical development to sales and product contracting. James currently serves on the Board of Directors and as a Member of the Audit Committee of Verona Pharma plc (Nasdaq: VRNA).

James is a CPA and holds a B.S in Accounting from Saint Joseph University and an MBA from Drexel University.

Headshot of BJ  Bormann
BJ Bormann
Independent, Non-executive Board Member

BJ Bormann is a professional with nearly 30 years of experience in academic and pharmaceutical science and biotechnology and pharmaceutical business development. She most recently served as the Vice President of Translational Science and Network Alliances for the Jackson Laboratory. In this role, Dr. Bormann worked to bring the innovations from the Jackson Laboratory faculty closer to patients by generating a series of collaborative relationships with industrial partners. Dr. Bormann’s previous work in the biotechnology area includes serving as CEO of Pivot Pharmaceuticals (OTC: PVOTF) as well as CEO of Supportive Therapeutics, LLC, a company developing a drug for the treatment of oral mucositis, a severe side effect to chemoradiation treatment in oncology patients.

Dr. Bormann has previously served as the CEO of Harbour Antibodies, based in the Netherlands, licensing transgenic mice that make human antibodies, as well as the Chief Business Advisor for NanoMedical Systems, Inc. of Austin, Texas, which licenses a unique implantable drug delivery device. Prior to these engagements, from 2007–2013, Dr. Bormann was Senior Vice President at Boehringer Ingelheim Pharmaceuticals, Inc., responsible for worldwide alliances, licensing, and business development. From 1996– 2007, she served in a number of positions at Pfizer, Inc., the last one being Vice President of Pfizer Global Research and Development and the worldwide Head of Strategic Alliances.

Dr. Bormann currently serves on the board of directors of various companies, including Supportive Therapeutics, LLC, the Institute for Pediatric Innovation, and Bioline RX (Nasdaq: BLRX). Dr. Bormann received her PhD in Biomedical Sciences from the University of Connecticut Health Center and her BS in Biology from Fairfield University. Dr. Bormann completed postdoctoral training at the Yale School of Medicine in the department of Pathology.

Committee Roles:
Chair of the Compensation Committee
Member of the Nominating Governance Committee
Headshot of Jeffrey W.  Sherman
Jeffrey W. Sherman
Independent, Non-executive Board Member

Jeffrey (Jeff) W. Sherman, MD, FACP, has more than 30 years of experience in the biopharmaceutical industry.  He was most recently the Chief Medical Officer and Executive Vice President at Horizon Therapeutics until its acquisition by Amgen.  Dr. Sherman also served on the Board of Directors of Strongbridge prior to its acquisition by Xeris Pharmaceuticals, Inc in 2021. Additionally, Dr. Sherman served previously on the Board of Directors of the Biotechnology Innovation Organization (BIO), Larimar Therapeutics and of Sorriso Pharmaceuticals, Inc. He is a member of a number of professional societies, a diplomat of the National Board of Medical Examiners and the American Board of Internal Medicine, and on the Board of Advisors of the Center for Information and Study on Clinical Research Participation. He previously held positions at pharmaceutical companies such as IDM Pharma, Inc., Takeda Global Research and Development, NeoPharm Inc., G.D. Searle, LLC/Pharmacia Corporation, and BristolMyers Squibb, and is a past board chair of the Drug Information Association.

Dr. Sherman received a B.A. in Biology from Lake Forest College and earned his M.D. from the Rosalind Franklin University of Medicine and Science/The Chicago Medical School. Dr. Sherman completed internship and residency programs at Northwestern University Feinberg School of Medicine, where he currently serves as an adjunct assistant professor, and a fellowship program at the University of California, San Francisco.

Committee Roles:
Member of the Compensation Committee
Member of the Nominating Governance Committee

Headshot of John  Shannon
John Shannon
Chief Executive Officer

John Shannon was appointed Chief Executive Officer in August 2024.  He joined Xeris in 2017 as Chief Operating Officer and was promoted to President in 2020.  Mr. Shannon has 35+ years of pharmaceutical and healthcare experience with a diverse background in sales, global and US marketing, operations and manufacturing, strategic planning, and business development.

Prior to Xeris, Mr. Shannon spent two years as Chief Executive Officer for Catheter Connections, Inc., a company focused on the development and commercialization of innovative vascular access products designed to protect patients from acquiring infections during intravenous infusion therapy. Catheter Connections, Inc. was acquired by Merit Medical in January 2016.

Before Catheter Connections, Mr. Shannon spent three years as Chief Commercial Officer for Durata Therapeutics, a biopharmaceutical company focused on the development and commercialization of differentiated therapeutic solutions to advance patient care in infectious disease and acute illnesses. Durata was acquired by Actavis (now Allergan) in November 2014. Mr. Shannon spent 10 years (2001–2011) at Baxter Healthcare, where he was General Manager, Global Hemophilia and Global Commercial Excellence; General Manager, US Biopharmaceuticals; Vice President, Marketing US Bioscience; and Vice President, Marketing US Renal. During his time at Baxter, he led the commercialization and drove the growth of two Baxter brands, ADVATE® and GAMMAGARD®, both of which now exceed revenues of $1 billion.

Prior to coming to Baxter, Mr. Shannon was Vice President, Marketing for Caremark. Before that, he was at Searle for 10 years; there, he held several positions, most notably Executive Director, Cardiovascular Global Commercialization, in which he was responsible for the commercial development and marketing of new cardiovascular products worldwide, and Senior Director of Cox-2 Global Commercialization, in which he led the worldwide launch and global marketing of Celebrex®. In addition, he spent 7 years at Bock Pharmacal Company, where he held various positions including Sales Representative, Sales Trainer, Sales Operations, Marketing, Strategic Planning, and Business Development.

Mr. Shannon holds a BS in Biology with an emphasis in Microbiology from Western Illinois University.