product pipeline
Xeris has developed a robust pipeline of development programs for extending currently marketed products into important new indications and uses. Our pipeline also launches new products utilizing our proprietary formulation technology platforms to support long-term product development and commercial success.
Pipeline includes products across the range of development
Product Candidate | Indication | Formulation Development Nonclinical Phase 1 Phase 2 Phase 3 In-review Marketed | |
---|---|---|---|
Gvoke® (US) (glucagon injection) | Formulation Development PreClinical Phase 1 Phase 2 Phase 3 In-Review Marketed | Severe hypoglycemia, or severe low blood sugar, occurs when your blood sugar gets so low that you need help to bring it back up. Sometimes people with very low blood sugar may have a hard time thinking straight or controlling their body, get very tired, refuse to eat, pass out, or even have a seizure. It is an emergency situation that needs to be treated immediately.* | |
Keveyis® (dichlorphenamide) | Formulation Development PreClinical Phase 1 Phase 2 Phase 3 In-Review Marketed | Primary Periodic Paralysis (PPP) is a rare genetic condition that affects muscles and causes episodes of muscle weakness and/or temporary paralysis, that can be progressive and debilitating. 1,2 | |
Ogluo® (UK/EU)** (glucagon) | Formulation Development Nonclinical Phase 1 Phase 2 Phase 3 In-Review Marketed | Severe hypoglycemia, or severe low blood sugar, occurs when your blood sugar gets so low that you need help to bring it back up. Sometimes people with very low blood sugar may have a hard time thinking straight or controlling their body, get very tired, refuse to eat, pass out, or even have a seizure. It is an emergency situation that needs to be treated immediately. * | |
Recorlev® (levoketoconazole) | Formulation Development PreClinical Phase 1 Phase 2 Phase 3 In-Review Marketed | Endogenous CS is a rare, serious endocrine disorder caused by chronic exposure to elevated levels of cortisol; left untreated, it can be fatal. Often the result of a benign tumor of the pituitary gland that tells the body to overproduce high levels of cortisol for a sustained period of time. CS results in physical and emotional signs and symptoms that are debilitating for those living with CS. It is most common among adults aged 30 to 50 years and is more prevalent in females, accounting for 70% of cases.* | |
Levothyroxine | Formulation Development Nonclinical Phase 1 Phase 2 Phase 3 In-Review Marketed | Hypothyroidism, also known as underactive thyroid disease, is a condition in which the thyroid gland does not create and release enough thyroid hormone into the bloodstream. Hypothyroidism may not cause noticeable symptoms in the early stages. Over time, untreated hypothyroidism can cause a number of health problems. *Patil N, Rehman A, Anastasopoulou C, Jialal I. Hypothyroidism. In: StatPearls. Treasure Island (FL): StatPearls Publishing; Updated February 18, 2024. Accessed September 27, 2024. https://www.ncbi.nlm.nih.gov/books/NBK519536/ | |
Beta Bionics | Glucagon for bi-hormonal pumps | Formulation Development Nonclinical Phase 1 Phase 2 Phase 3 In-Review Formulation Development | |
Amgen | Thyroid Eye Disease (Teprotumumab) | Formulation Development Nonclinical Phase 1 Phase 2 Phase 3 In-Review Formulation Development | |
Regeneron | Undisclosed | Formulation Development Nonclinical Phase 1 Phase 2 Phase 3 In-Review Formulation Development |
† Orphan Drug Designation
**Xeris has an exclusive agreement with Tetris Pharma Limited, a subsidiary of Arecor Therapeutics plc, for the commercialization of Ogluo® in the European Economic Area, United Kingdom, and Switzerland